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Live-Cell Fluorescence Imaging Chip
CIC-6F
Six-channel microfluidic imaging chip can use with a 170 µm optical bottom for confocal fluorescence microscopy, live-cell observation, blood cells, and micro-volume samples operation.
Bring Small Samples into an Imaging-Ready Microchannel
Live-Cell Fluorescence Imaging Chip is a six-channel microfluidic observation chip developed for fluorescence and high-magnification microscopy. Samples remain inside defined microchannels, allowing researchers to work with small volumes while keeping cells or blood cells in an imaging-friendly format.
Optical Bottom Designed for Confocal Microscopy
The chip uses a 170 µm optical bottom, corresponding to the standard 0.17 mm coverslip thickness commonly used for high-resolution microscopy. This design supports confocal fluorescence microscopy and other high-magnification imaging workflows.
Six Independent Channels for Efficient Experimental Design
Each chip contains six short channels, allowing up to six independent experiments or conditions on a single slide-format device. Standard pipettes can be used to introduce cell suspensions or blood samples, making the chip easy to integrate into routine laboratory workflows.
Feature
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Compatible with confocal fluorescence microscopy and high-magnification observation.
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170 µm optical bottom designed around standard microscopy optics.
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Six independent microfluidic channels on one chip.
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Supports observation, image capture, and video recording of rare or micro-volume samples.
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Allows for real-time observation of cellular drug responses.
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Supports live-cell and blood-cell observation and research.Use small sample volumes to help conserve cells and reagents.
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Use small sample volumes to help conserve cells and reagents.
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Samples are contained within microchannels rather than spread across a conventional flat slide.
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Compatible with standard pipettes for introducing cell suspensions or blood samples.
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Can be used for cell and microbial experiments within the microchannels.
Application
Confocal Fluorescence Microscopy
Designed for high-resolution fluorescence imaging where optical compatibility and controlled sample placement are important.
Live-Cell and Blood-Cell Observation
Supports direct microscopic observation of live cells and blood cells, including image capture and video recording.
Microbial and Cell-Based Experiments
The channels can be used as a compact environment for cell or microorganism observation and other microscopy-centered experimental workflows.
Micro-Volume and Precious Samples
The microchannel format helps reduce sample and reagent consumption, making it useful when cells or reagents are limited.
Real-Time Drug Responses
Enables the continuous monitoring of live-cell dynamic responses to drug treatments in real time.
Specification
Direction for Use
A general imaging workflow is provided below. Sample preparation, staining, incubation, and imaging conditions should be selected according to the experimental protocol.
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Prepare the cell suspension, blood sample, microorganism sample, or stained specimen according to the study protocol.
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Using a standard pipette, introduce the sample through the inlet and allow the microchannel to fill without trapping bubbles.
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Confirm that the sample is positioned in the observation region of the selected channel.
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Place Live-Cell Fluorescence Imaging Chip on the microscope stage and select the appropriate objective and imaging mode.
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For fluorescence experiments, use excitation, emission, exposure, and acquisition settings established for the fluorophore and microscope system.
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Capture images or video as required by the experiment.
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Use the remaining channels for additional replicates, conditions, or samples as appropriate.
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After completion, handle and dispose of the used chip according to the laboratory's biological-safety procedure.
Note: Recommended loading volume and incubation conditions are protocol-dependent.
